Tuesday, 6th February The 43rd Lorne Conference on Protein Structure and Function 2018
Breakfast
7:00AM - 8:30AM
Tuesday, 6th February
Lorne Central
Session 8: Membrane proteins
8:30AM - 10:30AM
Tuesday, 6th February
Auditorium
Chairs: Megan Maher & Sheena McGowan
- Time-resolved serial femtosecond crystallography studies at an X-ray free electron laser reveals structural changes in bacteriorhodopsin - Richard Neutze
- Specific and promiscuous ligand recognition by chemotaxis receptors. - Anna Roujeinikova
- T cell receptors have some more tricks up their sleeves. - Stephanie Gras
- The architecture of the membrane associated retromer-sorting nexin complex revealed by cryo-electron tomography - Brett Collins
- Recognition of Necl5 by the Natural Killer Cell Receptor CD96 - Felix A Deuss
Morning Tea/Coffee Break
10:30AM - 11:00AM
Tuesday, 6th February
Exhibition Hall
Session 9: Dynamics and movement
11:00AM - 1:10PM
Tuesday, 6th February
Auditorium
Chairs: Bostjan Kobe & Paul Gooley
- How is electrical signal generated? Structural and mechanistic investigations of Nav channels - Nieng Yan
- Observing the effect of host cell proteins on viral capsid disassembly at the single-molecule level - Till Böcking
- Role of dynamic cooperativity in the mechanism of hexameric M17 aminopeptidases - Nyssa Drinkwater
- Proteomic discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella - Christopher M Overall
- Tracking oligomeric transcription factor dynamics by pair correlation of molecular brightness (pCOMB) - Elizabeth Hinde
Lunch
1:10PM - 2:00PM
Tuesday, 6th February
Exhibition Hall
Student and Invited Speaker Lunch (Ticketed Event)
1:10PM - 2:30PM
Tuesday, 6th February
Horizons Room
Session 10: Poster Session C including refreshments
4:00PM - 6:00PM
Tuesday, 6th February
Exhibition Hall
- Structural and functional characterisation of the pseudokinase scaffold SgK269 - Ashleigh Kropp
- The interaction of the effector of type II secretion system in K. pneumoniae with macrophages. - Jiahui Li
- The Roc-COR domain of Leucine-rich repeat kinase 2 belongs to conventional Ras-like GTPases, not a GAD - Lung-Yu Liang
- The influence of mortise-tenon joints on OmpF stability - Jiansi Long
- Structural characterisation of the mitochondrial complex IV assembly factor, COA6 - Shadi Maghool
- Metal-dependent dynamic equilibrium: a mechanism for regulation of the Plasmodium M17 aminopeptidases? - Tess R Malcolm
- Assembly of β-barrels in the outer membrane; What is the role of BamC? - Eric Mandela
- Immunoreceptors as Therapeutic Targets for Alzheimer's and Parkinson's Disease - Jasmina Markulic
- Inhibition of Aspergillus fumigatus thioredoxin reductase by ebselen - Andrew C Marshall
- The development of a protein folding sensor to study molecular chaperones at the single molecule level - Nicholas Marzano
- A split EGFP complementation system for finding novel α-helical peptides that bind to LMO4 - Gabrielle McClymont
- Evolution of genes that enhance resistance to the antifungal defensin NaD1 - Amanda McColl
- Detecting protein-protein crosslinks formed during food processing - Hannah J McKerchar
- EmbB and GidB: Mutational Hotspots for Antibiotic Resistance in Mycobacterium tuberculosis - Eleni-Maria Michanetzi
- Kinact: a computational approach for predicting activating missense mutations in protein kinases - Carlos H.M. Rodrigues
- Crystal Structure of the SH2 Domain of the Lypmphocyte Adaptor Protein LNK (SH2B3) - Rhiannon Morris
- Are RuBisCO chaperone proteins required for the core assembly of cyanobacterial carboxysomes? - Nghiem D Nguyen
- Isolation of TOM complex from Drosophila flies for structural studies - Agalya Periasamy
- Cryo-EM structures of an ABC toxin complex in different states provide new clues to the mechanism of action - Sarah Piper
- Structural Insight of Arsenate Reductase in Chrysiogenes arsenatis, ArrX - Nilakhi Poddar
- DEAD-box RNA helicase DDX20 in redox-dependent regulation of Wnt/β-catenin signalling in triple-negative breast cancer - Sebastian Pohl
- Understanding the molecular consequences of genomic variation associated with drug resistance in Mycobacterium tuberculosis - Stephanie Portelli
- The Evolution of a Quantum Coherent Light Harvesting Apparatus: Selection for Efficiency or Merely a Spandrel. - Harry W Rathbone
- Revealing allosteric mechanisms of KLK4 inhibition through structural and dynamical characterisation - Blake T Riley
- Differences in aggregation behaviour between a recombinantly expressed synthetic DYW-type Pentatricopeptide Repeat protein and a native protein from Arabidopsis thaliana - Santana Royan
- Structural determination of Streptomyces antibioticus phospholipase D engineered to produce 1-phosphatidylinositol - Ariela Samantha
- Investigation of BCL-RAMBO, a poorly characterised BCL-2 family member - Kristen Scicluna
- Human Hsp27 is a redox-sensitive small heat-shock protein - Emily E Selig
- Activation of RIG-I by hairpin RNA - Neelam Shah
- An Integrated Pipeline to analyse the impact of coding mutations on protein structure and function - Vasishth Sidarala
- Predicting missense variant consequences using an integrated genomics and structural biology approach - Michael Silk
- Progress toward the biophysical and structural characterisation of the Neisserial capsule export machinery - Luke Smithers
- Reconstruction of ancestral LacI/GalR Family transcription factors - Matthew A Spence
- Investigating the structure of class III biotin protein ligases to understand biotinylation selectivity - Louise M Sternicki
- The long and short of DAH7PS: distinct quaternary structures of two type II isozymes from Pseudomonas aeruginosa - Oliver W Sterritt
- Early stage drug discovery in the australian cancer research foundation rational drug discovery centre - Brendan W Stevenson
- Copper resistance mechanisms in Salmonella - Pramod Subedi
- Understanding how proteostasis maladaptation relates to proteome aggregation under protein folding stress - Xiaojing Sui
- Cell envelope biosynthetic pathways as targets for novel antimicrobial drug design against Burkholderia pseudomallei and Neisseria meningitidis - Courtney M Sullivan
- Characterization of roles of auxiliary proteins in an ABC transporter complex implicated in maintenance of outer membrane lipid asymmetry in Escherichia coli - Shuhua Thong
- Investigating the structure and function of transmembrane domains in MARCH E3 ligases and single‑span receptors - Raphael Trenker
- NMR based determination of ligand binding conformations at α1-Adrenergic receptor subtypes - Tasneem Vaid
- Engineering a FRET-based biosensor for in-situ detection of D-serine - Vanessa Vongsouthi
- In-depth conformational study of the von Willebrand Factor D' domain using molecular dynamics simulations - Vishal Pandya
- MOLECULAR ARCHITECTURE OF THE E. FAECALIS ANTI-TERMINATION PROTEIN EUTV BOUND TO RNA - James Walshe
- The interaction of the effector of type II secretion system in K. pneumoniae with macrophages. - Jiahui Li
- Optimisation of EcDsbA inhibitors by fragment based drug design - Rebecca Whitehouse
- Engineering enzymes to perform targeted epigenetic modifications - James Woodmansey
- Contributions of the beta-barrel domain in the assembly of autotransporter Ag43 - Xiaojun Yuan
- Structural analysis of critical interactions in the replication machinery of rabies virus - Jingyu Zhan
- Structural characterisation of MlaD from A. baumannii - Jing Zhang
- Small molecule fluorogens for measuring proteostasis capacity in cells - Shouxiang Zhang
- Functional studies of a lipid A phosphoethanolamine transferase in pathogenic Neisseria - Katherine Lim
- Structural studies reveal the mechanism of nucleotide triphosphate promiscuity for Mycobacterium tuberculosis dethiobiotin synthetase: a novel antibiotic target - ANDREW THOMPSON
Dinner (own arrangements)
6:00PM - 7:45PM
Tuesday, 6th February
Session 11: Robin Anders Young Investigators Award session
7:45PM - 9:00PM
Tuesday, 6th February
Auditorium
Chairs: Melissa Call & James Murphy
Sponsored by:
- Plasticity of inter-protein contacts confers selectivity in ligand induced protein degradation - Eric S Fischer
- Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein - Christine Oellig
- Meet the carpenter: protease-mediated joinery - Joel Haywood
- Antibodies targeting the α1-α2 loop of pro-apoptotic effectors Bak and Bax induce or inhibit apoptosis-associated conformation change and pore formation - Sweta Iyer
Session12: Poster Session D - Including Happy Hour & Trade Display
9:00PM - 10:00PM
Tuesday, 6th February
Exhibition Hall
- A novel exosite peptide enhances binding of the SOCS2-SH2 domain to phosphorylated targets - Edmond Linossi
- Electrostatic interactions between Hendra virus matrix proteins are required for productive virus-like-particle assembly - YU CHIH LIU
- Inhibition of Antigen 43 autotransporter-mediated aggregation and biofilm formation - Alvin Lo
- Structural basis of Zn(II) acquisition by AdcAII in pneumococcus - Zhenyao Luo
- Immobilised enzymes on customisable micro solid phase extraction cartridges for proteolytic digests in minutes - Karen Duong
- Understanding the relevance of the two quaternary structures of light harvesting proteins from Hemiselmis andersenii. - Katharine A Michie
- Macromolecular Interactions Facility: Biophysical Analysis of Proteins and Macromolecules - Y Mok
- Rings, hoops, staples, hairpins and ladders hiding in protein hosts - Joshua S Mylne
- The structure and function of a bacterial sialic acid membrane transporter - Rachel North
- How does the MLKL pseudokinase domain control active state transition and oligomer formation during necroptotic cell death? - Emma J Petrie
- Structure and function of the OmpK37 porin from the outer membrane of Klebsiella pneumoniae - Andrea Rocker
- Maskless quantitative multi-protein photopatterning by PRIMO to orchestrate cellular microenvironment - Nandor Roczo
- Crystal Structure of Mycobacterium Tuberculosis Protein Kinase G - David Ruiz Carrillo
- Using enzyme assays and structures for high-throughput screening to discover inhibitors of rumen methanogens - Linley R Schofield
- Development of a 4-plex digital immunoassay for detection of Neurofilament-Light, Tau, Glial Fibrillary Acidic Protein and Ubiquitin c-Terminal Hydrolase L1 in blood and cerebrospinal fluid - Brenton Short
- Understanding random crystal screening with microseeding – how new strategies can improve productivity - Patrick Shaw Stewart
- Ticks from diverse genera encode chemokine-inhibitory evasin proteins - Martin Stone
- Structure and function of the TAM, a nanomachine responsible for the assembly of complex outer membrane proteins - Christopher J Stubenrauch
- Determining the transmembrane features of MARCH9 E3 ligase required for substrate down-regulation - Cyrus Tan
- Molecular basis for the maintenance of lipid asymmetry in the outer membrane of Escherichia coli - Kang Wei Tan
- Functional analysis of the bacterial β-barrel assembly machinery - Kher Shing Tan
- Structural studies of the M4 and M5 muscarinic acetylcholine receptors - David M Thal
- Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex - Mario Torrado del Rey
- PARD6A Promotes Migration and Invasion of Ovarian Cancer - Hanqing Liu
- Structural and functional investigations of the CzcD transporter from Streptococcus pneumoniae a member of the Cation Diffusion Facilitator family of metal efflux proteins - Saumya Udagedara
- Investigating the role of periplasmic chaperones on beta-lactamase folding - Grishma Vadlamani
- Cell-free based approach for rapid detection of protein-protein interactions - Shayli Varasteh Moradi
- Characterisation of peptide interactions that regulate protein kinase Cε activation - Dorothy C. Wai
- Protein labelling strategies at The National Deuteration Facility: isotopic labelling for NMR (2H/13C/15N) and neutron (2H) structural investigations - Karyn L Wilde
- Mapping genotype-phenotype associations of nsSNPs in coiled-coil oligomerization domains of the human proteome. - Merridee A Wouters
- Finding specificity in unexpected places: how non-specific ‘fuzzy’ interactions mediate the strain-specific recognition of a conserved malaria epitope - Christopher A. MacRaild
- SMART Chromatography™ - Re-writing the Rule Book for Purification - Craig Don Paul
- Molecular basis of polo-like kinase 4 in centriole duplication - Suk-Youl Park